Höhne was born in Augsburg and studied photography and AV media design at the Lazi Academy in Esslingen from 1989 to 1992, as well as acting at the Hochschule für Musik und Darstellende Kunst in Stuttgart from 1991 to 1995. Since 1994, she has appeared in TV and cinema productions in Germany and the USA and has been engaged at German municipal and state theaters and throughout Europe. As a voice-over artist, she is active in commercials, dubbing, audio books and radio plays.